Experimental Research on Staphylococcal L-form Induction

Correlation of staphylococcal bacteriophage types to L-form colony production.

The ability of 258 strains of Staphylococcus aureus and 132 strains of S. epidermidis to produce L-form colonies in a standard environment was investigated. Production of these colonies by S. aureus was correlated with their phage type. Phage type 7 strains produced L-form colonies in larger numbers and more consistently than those of phage type 80/81. No L-form colonies were produced by the S....

Microtubular structures in a stable staphylococcal L-form.

Microtubular structures, which were demonstrated as straight, dense-walled cylinders attached to cell membranes, were found in a stable staphylococcal L-form grown in the absence of antibiotic.

Induction of L-form Bacteria from Bacillus thuringiensis

Induction of L-form bacteria from Bacillus thuringiensis was investigated with the long-term view of their use as targeted biological control agents within plants. L-forms were successfully induced from B. thuringiensis subspecies israelensis 36-3 by preparing pour plates of exponential cultures in L-phase medium (LPM) containing 175 g ml -1 cephalosporin C. The induced L-forms were then subcul...

Induction and cultivation of staphylococcal L forms in the presence of methicillin.

Effect of thioridazine on experimental cutaneous staphylococcal infections.

BACKGROUND Some non-antibiotic drugs, such as the phenothiazine antipsychotic agents, may have antimicrobial activity. MATERIALS AND METHODS We sought to determine the in vivo antimicrobial effects of the phenothiazine thioridazine in two mouse models of Staphylococcus aureus skin infection. RESULTS Thioridazine significantly suppressed dissemination from skin to spleen and kidney after ino...